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50 Years of Integer Programming 1958-2008 (+ DVD)In 1958, Ralph E. Gomory transformed the field of integer programming when he published a paper that described a cutting-plane algorithm for pure integer programs and announced that the method could be refined to give a finite algorithm for integer programming. In 2008, to commemorate the anniversary of this seminal paper, a special workshop celebrating fifty years of integer programming was held in Aussois, ...
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Physics of the Life SciencesEach chapter has three types of learning aides for students: open-ended questions, multiple-choice questions, and quantitative problems. There is an average of about 50 per chapter. There are also a number of worked examples in the chapters, averaging over 5 per chapter, and almost 600 photos and line drawings.
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Data Correcting Algorithms in Combinatorial OptimizationData Correcting Approaches in Combinatorial Optimization focuses on algorithmic applications of the well known polynomially solvable special cases of computationally intractable problems. The purpose of this text is to design practically efficient algorithms for solving wide classes of combinatorial optimization problems. Researches, students and engineers will benefit from new bounds and branching rules in ...
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Conflict and Catastrophe MedicineThis 2nd updated edition is an entry-level text covering all aspects of deployment, not just medical or health-related, for use by health professionals in a resource-constrained environment brought about by local conflict or natural disasters. Since the 1st edition (2002), there have been seismic changes following the terrorist assault on the Twin Towers and the Pentagon. The Middle East, the Far East and parts ...
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Financial EconomicsFinancial economics is a fascinating topic where ideas from economics, mathematics and, most recently, psychology are combined to understand financial markets. This book gives a concise introduction into this field and includes for the first time recent results from behavioral finance that help to understand many puzzles in traditional finance. The book is tailor made for master and PhD students and includes ...
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TerraformingThis book proposes a sound and realistic exploration on the topic of terraforming. Often used as the narrative premise in science fiction novels, terraforming is the process by which an uninhabitable planet might be converted into one capable of supporting life. This book presents what is physically possible today and hints what might conceivably be put into practice in the next several hundred years.The author ...
Physiology and Biochemistry of Metal Toxicity and Tolerance in PlantsThe aim of this book is to give an overview of the most important aspects of physiological and biochemical basis for metal toxicity and tolerance in plants. The book is expected to serve as a reference to university and college teachers, students of plant sciences, environmental biology, environmental biotechnology, agriculture, horticulture, forestry, plant molecular biology, and genetics.
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Phosphoinositides in Subcellular Targeting and Enzyme ActivationCells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.
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Biostatistical MethodsLeading biostatisticians and biomedical researchers describe many of the key techniques used to solve commonly occurring data analytic problems in molecular biology, and demonstrate how these methods can be used in the development of new markers for exposure to a risk factor or for disease outcomes. Major areas of application include microarray analysis, proteomic studies, image quantitation, genetic susceptibility ...
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In Situ Detection of DNA Damage: Methods and ProtocolsIn Situ Detection of DNA Damage: Methods and Protocols, Vladimir Didenko and a panel of experts describe all the major in situ techniques for studying DNA damage and apoptosis, and how approaches originally designed to label apoptotic cells can be used for DNA damage analysis (and vice versa). The readily reproducible techniques presented here include all those designed to detect specific single and double-stranded ...
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Oxidative Stress and Antioxidant ProtocolsDonald Armstrong updates and expands his highly praised Free Radical and Antioxidant Protocols (Humana, 1998) with a collection of new and valuable methods for evaluating the pertubations in cell function resulting from increased oxidative stress. Presented in a user-friendly, step-by-step format, these readily reproducible techniques cover both free radical-derived and antioxidant biomarkers. The methodologies ...
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Single Nucleotide Polymorphisms: Methods and ProtocolsPui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), ...
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A Practical Approach to Microarray Data AnalysisThe book addresses the requirement of scientists and researchers to gain a basic understanding of microarray analysis methodologies and tools. It is intended for students, teachers, researchers, and research managers who want to understand the state of the art and of the presented methodologies and the areas in which gaps in our knowledge demand further research and development. The book is designed to be used ...
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Heavy Metal Stress in Plants. From Biomolecules to EcosystemsWhilst heavy metal phytotoxicity has been known for more than a century, it is astonishing that interest in the effects of heavy metals on organisms has only recently received added attention. Research in the past years, however, has confirmed the immense damage by metal pollution to plants, the soil and ultimately to humans. This completely updated and enlarged second edition gives a state-of-the art review ...
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Nano-OpticsA presentation of the most advanced application of optical near-field microscopy to studies of fine metallic structures and related surface plasmons.
Affinity Chromatography. Methods and ProtocolsThirty-eight years after its introduction, affinity chromatography remains a key tool in the armory of separation techniques available to separation and interaction scientists. Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic ...
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Apoptosis: Techniques and ProtocolsIn this revised and expanded second edition, seasoned experts describe in step-by-step detail their best state-of-the-art techniques for studying neuronal cell death. These readily reproducible methods solve a wide variety of research problems, including the detection of the key proteins involved in neuronal apoptosis (Bax protein, cytochrome c, and caspases), the direct assessment of the role of pro-apoptotic ...
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Molecular Cytogenetics: Protocols and ApplicationsYao-Shan Fan and a panel of senior scientists and pioneering researchers describe in step-by-step style the leading FISH techniques and those molecular technologies beyond FISH available for diagnostic services in genetics and oncology. The methods include labeling FISH probes for DNA and RNA targets, fluorescence genotyping, CGH microarray, spectral karyotyping/multicolor FISH, and primed in situ labeling. ...
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Handbook of Multilevel AnalysisThis book presents the state of the art in multilevel analysis, with an emphasis on more advanced topics. These topics are discussed conceptually, analyzed mathematically, and illustrated by empirical examples. Multilevel analysis is the statistical analysis of hierarchically and non-hierarchically nested data. The simplest example is clustered data, such as a sample of students clustered within schools. Multilevel ...
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